Crop production in the Fanteakwa District is predominantly rainfed, exposing this major livelihood activity to the variability or change in rainfall pattern. The net potential effect of severe changes in rainfall pattern is the disruption in crop production leading to food insecurity, joblessness, and poverty. As a major concern to food production in Ghana, this study seeks to show the relationship between the production of major crops and rainfall distribution pattern in the Worobong Agroecological Area (WAA) relative to food security in the face of climate change.