This work was carried out to evaluate organ weight and histological changes in 24 buck rabbits subjected to Aspilia africana leaves supplemented with zinc gluconate. The bucks were divided into four equal groups. Each treatment was replicated three times in a completely randomized design. Treatment group one (T1) was fed concentrate plus conventional forages with 0.0mg zinc gluconate. Treatments 2, 3 and 4 were fed concentrate with 0.0mg zinc gluconate, 100mg zinc gluconate and 150mg zinc gluconate, respectively.