This report aims at inspiring strategic thinking and actions to transform agrifood systems towards a sustainable, resilient and inclusive future, by building on both previous reports in the same series as well as on a comprehensive corporate strategic foresight exercise that also nurtured FAO Strategic Framework 2022–31. It analyses major drivers of agrifood systems and explores how their trends could determine alternative futures of agrifood, socioeconomic and environmental systems. The fundamental message of this report is that it is still possible to push agrifood systems along a pattern of sustainability and resilience, if key “triggers” of transformation are properly activated.