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Climate change has direct and indirect impact on human health. The indirect impact includes Malnutrition caused by food insecurity. The population of the Sahel region of Cameroon continuously experiences an increasing level of malnutrition, partly due to the impact of climate change since harsh climatic conditions leading to extreme drought; have a negative influence on agriculture. In particular, the extreme drought conditions lead to a reduction in agricultural production an important parameter of food security. This review paper assesses the impact of climate change on food security which leads to an increase malnutrition in this region. It will help to suggest measures to raise awareness on climate change, food security and malnutrition. Keywords: Sahel, Climate Change, malnutrition, food security, agriculture, Cameroon.